JoVE Journal
Cancer Research
Cancer Research
This content is Open Access.
将斑马鱼小儿脑肿瘤移植入免疫能力的宿主,用于长期研究肿瘤细胞行为和药物反应
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Article
DOI:
10.3791/55712-v
•
09:43 min
•
May 17th, 2017
将斑马鱼小儿脑肿瘤移植入免疫能力的宿主,用于长期研究肿瘤细胞行为和药物反应
May 17th, 2017
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Mattie J. Casey*1, Katarzyna Modzelewska*1, Daniela Anderson1, James Goodman1, Elena F. Boer1, Laura Jimenez1, Douglas Grossman1,2, Rodney A. Stewart1
1Department of Oncological Sciences and Huntsman Cancer Institute, University of Utah School of Medicine, 2Department of Dermatology, University of Utah Health Sciences Center, Salt Lake City
* These authors contributed equally
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
癌细胞的移植是识别癌症机制和治疗反应的重要工具。目前的技术取决于免疫力不足的动物。在这里,我们描述了一种将斑马鱼肿瘤细胞移植到免疫感受态胚胎中的方法,用于长期分析肿瘤细胞行为和体内药物反应。