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Overaccumulation Ileectomy-induzierten Galle im Darm der Maus
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Overaccumulation Ileectomy-induzierten Galle im Darm der Maus

Article DOI: 10.3791/55728-v • 06:55 min • August 21st, 2017
August 21st, 2017 •
*1,2,3, 1,2, 1,2, *1,2
1Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University, 2Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, 3Institute for Transformative Molecular Medicine, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center
* These authors contributed equally

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Dünndarm-abhängige Gallensäure Resorption und Feedback-Hemmung der hepatischen Gallensäure Synthese ist wichtig für systemische Homöostase und Gesundheit. In dieser Studie beschreiben wir ein Mausmodell für ileale Resektion, Ileectomy-induzierten Galle Malabsorption, Overaccumulation und Toxizität im Darm der Maus zu bewerten.

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Ausgabe 126 Ileectomy Maus Krankheitsmodell Gewebe Kommunikation Medizin Fibroblasten-Wachstumsfaktor 15 (FGF15) Gallensäure Rückresorption kurzes Darmsyndrom
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