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JoVE Journal Bioengineering
Glycoengineering metabolica di acido sialico utilizzando N-acil-per volta Mannosamines
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Glycoengineering metabolica di acido sialico utilizzando N-acil-per volta Mannosamines

Article DOI: 10.3791/55746-v • 12:06 min • November 25th, 2017
November 25th, 2017 •
1,2, 3
1Max von Pettenkofer-Institut & Genzentrum, Virologie, Nationales Referenzzentrum für Retroviren, Medizinische Fakultät, LMU München, 2Institut für Laboratoriumsmedizin, klinische Chemie und Pathobiochemie, Charité - Universitätsmedizin Berlin, 3Institut für Physiologische Chemie, Martin-Luther-Universität Halle-Wittenberg

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Acido sialico è una tipica unità di monosaccaride trovata nei glycoconjugates. È coinvolto in una pletora di interazioni cellulari e molecolari. Qui presentiamo un metodo per modificare l'espressione di superficie acido sialico cellulare utilizzando glycoengineering metabolica con N- monosaccaridico derivati.

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Bioingegneria problema 129 acido sialico acido polisialico cromatografia liquida ad alte prestazioni coltura cellulare glycoengineering metabolica ingegneria metabolica oligosaccaride
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