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Journal / Genetics / 在慢性淋巴细胞性白血病患者中使用甲基CpG结合域捕获法进行综合DNA甲基化分析…
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JoVE Journal Genetics
在慢性淋巴细胞性白血病患者中使用甲基CpG结合域捕获法进行综合DNA甲基化分析
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在慢性淋巴细胞性白血病患者中使用甲基CpG结合域捕获法进行综合DNA甲基化分析

Article DOI: 10.3791/55773-v • 13:21 min • June 16th, 2017
June 16th, 2017 •
1, 2
1Department of Medical Genetics, Institute of Biomedicine, Gothenburg University, 2Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Gothenburg University

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Summary
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该工作描述了优化的甲基CpG结合结构域（MBD）测序方案和用于鉴定慢性淋巴细胞性白血病（CLL）患者中差异甲基化CpG富集区的计算管道。

Tags

遗传学，第124期DNA甲基化，甲基CpG DNA结合域蛋白，差异甲基化区域，下一代测序，蛋白质编码和非编码基因，慢性淋巴细胞白血病
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