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Immunology and Infection

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JoVE Journal Immunology and Infection
Screening tests karakteriseren roman Endothelial toezichthouders die betrokken zijn bij de ontstekingsreactie
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Screening tests karakteriseren roman Endothelial toezichthouders die betrokken zijn bij de ontstekingsreactie

Article DOI: 10.3791/55824-v • 12:50 min • September 15th, 2017
September 15th, 2017 •
1, 1, 1, *1, *1
1Pharmacological Therapies Unit, Research Institute for Rare Diseases, Institute of Health Carlos III
* These authors contributed equally

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Vasculaire endotheel bepaalt strak leukocyte werving. Onvoldoende leukocyte extravasation draagt bij tot de inflammatoire ziekten bij de mens. Daarom is zoeken naar nieuwe regelgevende elementen van endothelial activering om te ontwerpen van verbeterde therapieën voor inflammatoire aandoeningen. Hier beschrijven we een uitgebreide methodologie om te karakteriseren roman endothelial regelgevers die leukocyte handel tijdens ontsteking kunnen wijzigen.

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Immunologie kwestie 127 endotheliale cellen inflammatoire respons LPS (lipopolysaccharide) celadhesie-moleculen cytokines chemokines screening tests leukocyten hechting.
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