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Journal / Genetics / ChEC-seq ile Protein-DNA Etkileşimlerinin Genom…
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Genetics

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JoVE Journal Genetics
ChEC-seq ile Protein-DNA Etkileşimlerinin Genom Boyunca Haritalandırılması
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ChEC-seq ile Protein-DNA Etkileşimlerinin Genom Boyunca Haritalandırılması

Article DOI: 10.3791/55836-v • 10:43 min • June 3rd, 2017
June 3rd, 2017 •
1, 2
1Basic Sciences Division, Fred Hutchinson Cancer Research Center, 2Department of Biology, Indiana University

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Mikrokokal nükleaz (MNase) füzyon proteinleri ile genom çapında protein bağlama bölgelerinin haritalanması için bir kromatin immünopresipitasyon (ChIP) -orthogonal yöntem olan yüksek verimli sekanslama (ChEC-seq) ile birleşince, kromatin endojen bölünmeyi tarif ederiz.

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Genetics ChEC-seq ChIP-seq transkripsiyon genom çapında Arabulucu,
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