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Intranasal levering af terapeutiske stamceller til glioblastom i en musemodel
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Intranasal levering af terapeutiske stamceller til glioblastom i en musemodel

Article DOI: 10.3791/55845-v • 09:57 min • June 4th, 2017
June 4th, 2017 •
1, 1, 1, 1
1Department of Neurological Surgery, Feinberg School of Medicine, Northwestern University

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Stamceller er lovende terapeutiske bærere til at behandle hjernetumorer på grund af deres indre tumor tropisme. Ikke-invasiv intranasal stamcelleudlevering omgår blodhjernebarrieren og viser stærkt potentiale for klinisk oversættelse. Denne artikel opsummerer de grundlæggende principper for intranasal stamcelle levering i en musemodel af gliom.

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Medicin udgave 124 hjerne tumor stamceller oncolytic virus genetisk modifikation hypoxi intranasal levering
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