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JoVE Journal Neuroscience
En protokol til måling af Cue reaktivitet i en rotte Model af kokain brug lidelse
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En protokol til måling af Cue reaktivitet i en rotte Model af kokain brug lidelse

Article DOI: 10.3791/55864-v • 07:51 min • June 18th, 2018
June 18th, 2018 •
*1,2,3, *1,4,5, 1,6, 1,6, 1,6, 1,6, 1,3,4
1Center for Addiction Research, University of Texas Medical Branch, 2Institute for Translational Sciences, University of Texas Medical Branch, 3Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, 4Department of Neurology, University of Texas Medical Branch, 5Department of Pathology, University of Texas Medical Branch, 6Department of Pharmacology and Toxicology, University of Texas Medical Branch
* These authors contributed equally

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Cue reaktivitet er udtænkt som følsomhed over for cues forbundet med medikamenter oplevelser, der bidrager til trang og tilbagefald i afholdende mennesker. Cue reaktivitet er modelleret i rotter ved måling attentional orientering mod drug-associeret stikord, der resulterer i appetitive tilgang adfærd i en cue reaktivitet test efter selvforvaltning og tvunget afholdenhed.

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Neurovidenskab sag 136 kokain stof brug lidelse selvforvaltning Cue reaktivitet Rats afholdenhed Cue tilbagefald Operant conditioning stofmisbrug narkotika-søger translationel
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