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JoVE Journal Cancer Research
Identifikation og karakterisering af metastatisk faktorer af genoverførsel i romanen RIP-Tag; RIP-tva Murine Model
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Identifikation og karakterisering af metastatisk faktorer af genoverførsel i romanen RIP-Tag; RIP-tva Murine Model

Article DOI: 10.3791/55890-v • 09:03 min • October 16th, 2017
October 16th, 2017 •
1, 1, 1
1Department of Pathology and Laboratory Medicine, Weill Cornell Medicine

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Vi præsenterer en protokol for at demonstrere en roman somatiske gen overførselssystem udnytter RIP-Tag; RIP-tva musen model til at studere funktionen af gener i metastaser. De aviær retrovira leveres intracardiacally for at sikre overførsel af gener til præmaligne, noninvasive læsioner i bugspytkirtlen β celler i voksen mus.

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Kræftforskning spørgsmålet 128 mus model metastase RCAS somatiske genoverførsel RIP-Tag RIP-tva
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