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JoVE Journal Cancer Research
Identifiering och karakterisering av metastaserande faktorer av genöverföring i romanen RIP-taggen; RIP-tva murina modell
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Identifiering och karakterisering av metastaserande faktorer av genöverföring i romanen RIP-taggen; RIP-tva murina modell

Article DOI: 10.3791/55890-v • 09:03 min • October 16th, 2017
October 16th, 2017 •
1, 1, 1
1Department of Pathology and Laboratory Medicine, Weill Cornell Medicine

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Vi presenterar ett protokoll för att visa en del av ett system för överföring av somatisk gen utnyttja RIP-Tag; RIP-tva musmodell att studera funktionen av gener i metastaser. De aviär retrovirus levereras intracardiacally för att säkerställa genöverföring till pre-maligna, noninvasiv lesioner av pankreas β-celler i vuxna möss.

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Cancerforskning fråga 128 mus modell metastaser RCAS somatiska genöverföring RIP-Tag RIP-tva
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