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Journal / Immunology and Infection / Generazione di varianti di fuga di neutralizzare…
JoVE Journal
Immunology and Infection

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JoVE Journal Immunology and Infection
Generazione di varianti di fuga di neutralizzare l'Influenza Virus anticorpi monoclonali
T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
Journal (Immunology and Infection)
T and B Cell Receptor Immune Repertoire Analysis using Next-generation Sequencing
Treatment of the Monocyte-Derived Dendritic Cells (mo-DCs) with Sialidase
Journal (Immunology and Infection)
Treatment of the Monocyte-Derived Dendritic Cells (mo-DCs) with Sialidase
 
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Generazione di varianti di fuga di neutralizzare l'Influenza Virus anticorpi monoclonali

Article DOI: 10.3791/56067-v • 07:55 min • August 29th, 2017
August 29th, 2017 •
1,2, 1,2, 1,2, 1,2, 3, 3, 1, 1
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3The Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago

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Descriviamo un metodo con cui identifichiamo residui critici necessari per l'associazione di anticorpi monoclonali umani o murini destinati l'emoagglutinina virale del virus di riossidazione A. Il protocollo può essere adattato ad altre glicoproteine di superficie del virus e loro corrispondenti anticorpi neutralizzanti.

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Immunologia problema 126 virus dell'Influenza anticorpi monoclonali varianti di fuga microbiologia virologia
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