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Journal / Immunology and Infection / Generasjon av Escape varianter av nøytralisere…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Generasjon av Escape varianter av nøytralisere influensa Virus monoklonale antistoffer
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Generasjon av Escape varianter av nøytralisere influensa Virus monoklonale antistoffer

Article DOI: 10.3791/56067-v • 07:55 min • August 29th, 2017
August 29th, 2017 •
1,2, 1,2, 1,2, 1,2, 3, 3, 1, 1
1Department of Microbiology, Icahn School of Medicine at Mount Sinai, 2Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 3The Department of Medicine, Section of Rheumatology, The Knapp Center for Lupus and Immunology Research, The University of Chicago

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Vi beskriver en metode som vi identifisere kritiske rester kreves for binding av menneskelige eller murine monoklonale antistoffer som mål i viral hemagglutinin av influensa A virus. Protokollen kan tilpasses andre virus overflate glykoproteiner og deres tilsvarende nøytraliserende antistoffer.

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Immunologi problemet 126 influensavirus monoklonale antistoffer rømme varianter mikrobiologi virologi
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