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筛选生物活性纳米颗粒在噬菌体免疫细胞中的Toll样受体信号传导抑制剂
 
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筛选生物活性纳米颗粒在噬菌体免疫细胞中的Toll样受体信号传导抑制剂

Article DOI: 10.3791/56075-v 09:51 min July 26th, 2017
July 26th, 2017

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Summary

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Toll样受体(TLR)信号在许多人类炎性疾病的病理生理学中起着重要作用,并且预期在许多炎症状态下调节生物活性纳米颗粒的TLR应答是有益的。基于THP-1细胞的报道细胞提供了一个通用和强大的筛选平台,用于鉴定TLR信号传导的新型抑制剂。

Tags

医学,第125期,生物活性纳米颗粒,纳米药物筛选,金纳米颗粒,肽,toll​​样受体,TLR抑制剂,报道细胞
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