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JoVE Journal Developmental Biology
Evaluering af skade-induceret gulne og In Vivo omprogrammering i den skeletmuskulatur
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Evaluering af skade-induceret gulne og In Vivo omprogrammering i den skeletmuskulatur

Article DOI: 10.3791/56201-v • 09:14 min • October 26th, 2017
October 26th, 2017 •
1, 1, 1
1Cellular Plasticity & Disease Modelling, Department of Developmental & Stem Cell Biology, CNRS UMR 3738, Institut Pasteur

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Her præsenterer vi en detaljeret protokol til at registrere både senescent og pluripotente stamceller i skeletmuskulatur ved skade mens inducerende i vivo omprogrammering. Denne metode er velegnet til evaluering af cellulære gulne rolle under vævsregeneration og omprogrammering i vivo.

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Udviklingsmæssige biologi spørgsmålet 128 cellulære gulne i vivo omprogrammering pluripotente stamceller omprogrammerbar musemodel muskelskader cardiotoxin regeneration gulne-associerede β-galactosidase farvning
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