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Neuroscience

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JoVE Journal Neuroscience
Müller Glia celle aktivering i en Laser-indusert Retinal degenerasjon og Regeneration modell i sebrafisk
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Müller Glia celle aktivering i en Laser-indusert Retinal degenerasjon og Regeneration modell i sebrafisk

Article DOI: 10.3791/56249-v • 06:27 min • October 27th, 2017
October 27th, 2017 •
1,2,3, 1, 1,2,3, 1, 1,2
1Department of Ophthalmology, University Hospital of Bern, University of Bern, 2Department of Clinical Research, University of Bern, 3Graduate School for Cellular and Biomedical Sciences, University of Bern

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Sebrafisk er en populær dyr modell å studere mekanismer for retinal degenerasjon/gjenfødelse virveldyr. Denne protokollen beskriver en metode for å indusere lokaliserte skade forstyrre ytre netthinnen med minimal skade indre netthinnen. Senere, overvåker vi i vivo retinal morfologi og Müller glia respons gjennom netthinnens gjenfødelse.

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Nevrobiologi problemet 128 mobilnettet biologi sebrafisk laserbehandling netthinnen degenerasjon gjenfødelse Müller celler optical coherence tomografi
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