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Journal / Bioengineering / Tillverkning och validering av en orgel-on-chip…
JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Tillverkning och validering av en orgel-on-chip System med integrerad elektroder direkt kvantifiera Transendothelial resistans
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Tillverkning och validering av en orgel-on-chip System med integrerad elektroder direkt kvantifiera Transendothelial resistans

Article DOI: 10.3791/56334-v • 10:51 min • September 26th, 2017
September 26th, 2017 •
1, 1, 1,2, 3, 1, 1, 1
1BIOS Lab on a Chip group, MIRA Institute for Biomedical Technology and Technical Medicine, MESA+ Institute for Nanotechnology and Max Planck Center for Complex Fluid Dynamics, University of Twente, 2Microsystems, Eindhoven University of Technology, 3Applied Stem Cell Technologies, MIRA Institute for Biomedical Technology and Technical Medicine, University of Twente

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Denna publikation beskriver tillverkning av en orgel-on-chip-enhet med integrerad elektroder för direkt kvantifiering av transendothelial resistans (TEER). För validering, den blood - brain barriären var härmade inuti mikroflödessystem enheten och dess barriärfunktion övervakades. De presenteras metoderna för elektrod integration och direkta TEER kvantifiering är allmänt tillämpliga.

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Biomedical Engineering problemet 127 organ-på-chips mikrofabrikation transendothelial elektriskt motstånd transepithelial resistans blod - hjärnbarriären mikrofluidik
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