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JoVE Journal
Immunology and Infection

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Overlappende peptid biblioteket tilordne Qa-1 Epitopes i et Protein
 
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Overlappende peptid biblioteket tilordne Qa-1 Epitopes i et Protein

Article DOI: 10.3791/56401-v 08:04 min December 20th, 2017
December 20th, 2017

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Summary

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Click here for the English version.

QA-1 (HLA-E i menneskelig) tilhører en gruppe av ikke-klassiske store histocompatibility kompleks 1b molekyler. Immunisering med Qa-1-bindende epitopes har vist seg å øke vev-spesifikk immun regulering og forbedre flere autoimmune sykdommer. Her beskriver vi en overlappende peptid biblioteket strategi for identifikasjon av Qa-1 epitopes i et protein.

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Immunologi problemet 130 overlappende peptid Qa-1 nonclassical store histocompatibility kompleks HLA-E immun regulering immun overvåking
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