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Un metodo pratico per estrazione ed analisi con cromatografia liquida dei neurotrasmettitori della catecolamina e loro metaboliti
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Un metodo pratico per estrazione ed analisi con cromatografia liquida dei neurotrasmettitori della catecolamina e loro metaboliti

Article DOI: 10.3791/56445-v • 13:35 min • March 1st, 2018
March 1st, 2018 •
1, 3, 4, 1, 2
1School of Public Health of Southeast University, Laboratory of Environment and Biosafety Research Institute of Southeast University in Suzhou, 2Key Laboratory of Child Development and Learning Science (Ministry of Education), School of Biological Science & Medical Engineering, Southeast University, 3School of Public Health, Tianjin Medical University, 4British Columbia Academy, Nanjing Foreign Language School

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Vi presentiamo una comoda estrazione in fase solida accoppiata alla cromatografia liquida (HPLC) con rivelazione elettrochimica (ECD) per la determinazione simultanea di tre neurotrasmettitori di monoammina e due dei loro metaboliti nelle urine dei bambini. Identifichiamo anche il metabolita MHPG come potenziale biomarcatore per la diagnosi precoce del danno cerebrale per neonati.

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Chimica problema 133 catecolamine corona polimerico nanofibre elettrofilate estrazione in fase solida fibra pranzo (PFSPE) cromatografia liquida ad alta pressione con rilevazione elettrochimica (HPLC-ECD) i neonati ad alto rischio
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