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Evaluatie van de In Vitro DNA schade, met behulp van komeet Assay

Article DOI: 10.3791/56450-v • 10:43 min • October 11th, 2017
October 11th, 2017 •
1,2, 1, 1
1Neuro-Oncology Branch, Center for Cancer Research, National Cancer Institute, 2Basic Medical Science Department, Zunyi Medical College-Zhuhai Campus

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De bepaling van de komeet is een efficiënte methode om op te sporen DNA schade met inbegrip van single- en double-stranded DNA breekt. We beschrijven alkalisch en neutraal komeet testen voor het meten van DNA-beschadiging in kankercellen het therapeutische effect van chemotherapie te beoordelen.

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Celbiologie kwestie 128 Chemo-gevoeligheid glioma DNA-beschadiging komeet assay eencellige elektroforese assay chemotherapie genotoxiciteit temozolomide olaparib PARP
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