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JoVE Journal Bioengineering
Griffithsin 修饰纤维支架预防性传播感染的制备与表征
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Griffithsin 修饰纤维支架预防性传播感染的制备与表征

Article DOI: 10.3791/56492-v • 12:21 min • October 31st, 2017
October 31st, 2017 •
*1, *2,3, 2,3,4,5
1Department of Chemistry, University of Louisville, 2Department of Pharmacology and Toxicology, University of Louisville, 3Center for Predictive Medicine, University of Louisville, 4Department of Microbiology and Immunology, University of Louisville, 5Department of Bioengineering, University of Louisville
* These authors contributed equally

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这份手稿描述了制造和表征 Griffithsin 修饰聚 (乳酸-羟基酸) 纺纤维的程序, 证明有效的粘合剂和抗病毒活性对抗人体免疫缺陷病毒1型感染体外。本文介绍了用于合成、表面修饰和表征表面改性纤维 Griffithsin 的形态、共轭和解吸的方法。

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生物工程 问题 128 纺纤维 性传播感染 人体免疫缺陷病毒 表面修饰 杀微生物剂 Griffithsin 聚 (乳酸羟基酸)
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