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Utilizando um dispositivo microfluídica para estimulação mecânica e alta resolução de imagem de c. elegans
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Utilizando um dispositivo microfluídica para estimulação mecânica e alta resolução de imagem de c. elegans

Article DOI: 10.3791/56530-v • 10:39 min • February 19th, 2018
February 19th, 2018 •
*1, *1,2, 1,2, 1,2,3, 1,2, 4
1Department of Molecular and Cellular Physiology, Stanford University, 2Department of Mechanical Engineering, Stanford University, 3Department of Bioengineering, Stanford University, 4Group of Neurophotonics and Mechanical Systems Biology, The Institute of Photonic Sciences (ICFO)
* These authors contributed equally

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Novas ferramentas para pesquisa de mechanobiology são necessários para compreender o estresse mecânico como ativa vias bioquímicas e elicia respostas biológicas. Aqui, vamos mostrar um novo método para a estimulação mecânica seletiva dos animais imobilizados com uma armadilha de microfluidic permitindo imagens de alta resolução de respostas celulares.

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Neurociência questão 132 microfluídica macio-litografia c. elegans mechanobiology mechanosensation dinâmica de cálcio
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