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JoVE Journal Immunology and Infection
Acidi grassi saturi indurre la morte delle cellule del macrofago Ceramide-collegato
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Acidi grassi saturi indurre la morte delle cellule del macrofago Ceramide-collegato

Article DOI: 10.3791/56535-v • 08:26 min • October 31st, 2017
October 31st, 2017 •
1, 1, 1, 1
1Department of Microbiology and Immunology, University of Louisville

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Un metodo semplice per preparare BSA-degli acidi grassi coniugati e illustriamo un metodo semplice per derivare macrofagi murini primari da cellule del midollo osseo. Allora dimostriamo che gli acidi grassi saturi può indurre la morte delle cellule del macrofago, e tale morte delle cellule è associato positivamente con accumulo cellulare di ceramide livelli.

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Macrofagi di immunologia problema 128 derivate da midollo osseo BSA (albumina di siero bovino) saturi acidi grassi acido palmitico acido stearico ceramide morte delle cellule
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