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In Vitro Misurazione di enzima per Test farmacologici Chaperone reattività in Fabry e malattia di Pompe

Article DOI: 10.3791/56550
December 20th, 2017 •
1, 1, 1, 2, 2, 1,3
1Albrecht-Kossel-Institute, University Rostock Medical Center, 2Department of Biology, University Federico II, 3Centogene AG

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December 20th, 2017

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C'è una domanda per fare pre-clinica test per una nuova classe di farmaci "orfani" chiamato chaperoni farmacologici riproducibile, veloce ed efficiente. Abbiamo sviluppato un test cellulari semplice, altamente standardizzate e versatile cultura alla schermata per i pazienti eleggibili come pure droghe romanzo chaperoni farmacologici.

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