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JoVE Journal Developmental Biology
Rask påvisning av Neurodevelopmental fenotyper i menneskelig Neural Precursor celler (NPC)
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Rask påvisning av Neurodevelopmental fenotyper i menneskelig Neural Precursor celler (NPC)

Article DOI: 10.3791/56628-v • 10:47 min • March 2nd, 2018
March 2nd, 2018 •
*1, *1, 1, 2, 3, 3, 4, 5, 2, 1
1Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 2Center for Advanced Biotechnology and Medicine, Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 3The Child Health Institute of NJ, Department of Obstetrics, Gynecology, and Reproductive Services, Rutgers Robert Wood Johnson Medical School, 4The Child Health Institute of NJ, Department of Neuroscience and Cell Biology, Rutgers Robert Wood Johnson Medical School, 5Department of Genetics, Rutgers University
* These authors contributed equally

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Neurodevelopmental prosesser som spredning, migrering og neurite resultatet er ofte opprørt i nevropsykiatriske sykdommer. Derfor presenterer vi for å raskt og reproduserbar vurdere prosessene neurodevelopmental i menneskelig iPSC-avledet NPCer. Disse protokollene kan også vurdering av virkningene av relevante vekstfaktorer og therapeutics på NPC-utvikling.

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Utviklingspsykologi biologi problemet 133 neurodevelopment utviklingspsykologi biologi neural precursor celler iPSC hjernesykdom autisme vekstfaktorer spredning neurite utvekst celle migrasjon
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