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Bioengineering

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JoVE Journal Bioengineering
Metodikk for Biomimetic kjemiske Neuromodulation av rotte Netthinne med signalstoffet glutamat In Vitro
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Metodikk for Biomimetic kjemiske Neuromodulation av rotte Netthinne med signalstoffet glutamat In Vitro

Article DOI: 10.3791/56645-v • 12:56 min • December 19th, 2017
December 19th, 2017 •
1, 2, 1
1Department of Mechanical and Industrial Engineering, University of Illinois at Chicago, 2Department of Biomedical Engineering, Northwestern University

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Denne protokollen beskriver en ny metode for å undersøke en form for kjemisk neurostimulation wholemount rotten Netthinne i vitro med signalstoffet glutamat. Kjemisk neurostimulation er et lovende alternativ til den konvensjonelle elektrisk neurostimulation retinal neurons for behandling av irreversible blindhet forårsaket av photoreceptor degenerative sykdommer.

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Bioteknologi problemet 130 kjemiske stimulering netthinnen photoreceptor degenerasjon neuromodulation netthinnen protese glutamat nevrotransmitter kjemiske synapse multielectrode array kunstige neurostimulation kunstige synapse chip
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