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Journal / Immunology and Infection / Rumsliga och tidsmässiga kontroll av…
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Immunology and Infection

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JoVE Journal Immunology and Infection
Rumsliga och tidsmässiga kontroll av T-cellsaktivering med hjälp av en Photoactivatable-Agonist
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Rumsliga och tidsmässiga kontroll av T-cellsaktivering med hjälp av en Photoactivatable-Agonist

Article DOI: 10.3791/56655-v • 07:48 min • April 25th, 2018
April 25th, 2018 •
1,2, 1
1Immunology Program, Memorial Sloan-Kettering Cancer Center, 2Weill-Cornell Graduate School of Medical Sciences

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Det här protokollet beskriver en imaging-baserad metod för att aktivera T-lymfocyter som använder photoactivatable peptid-MHC, möjliggör exakt spatiotemporal kontroll av T-cellsaktivering.

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Immunologi och infektion fråga 134 T-lymfocyter T-Cell Receptor (TCR) signaltransduktion Cell polaritet Centrosome Fotokemi Major Histocompatibility Complex (Pmhc) Centrosome totalreflexion mikroskopi (Frida) immunologi Cell Biologi
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