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JoVE Journal
Immunology and Infection

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建立高通量筛选平台评估乳腺癌 HER2 基因扩增的异质性
 
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建立高通量筛选平台评估乳腺癌 HER2 基因扩增的异质性

Article DOI: 10.3791/56686-v 11:34 min December 5th, 2017
December 5th, 2017

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Summary

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HER2-positive 细胞的异质分布可以在乳腺癌的一个子集中观察到, 并产生临床难题。在这里, 我们介绍了一个可靠的和成本-有效的协议, 以定义, 量化, 并比较 HER2 内肿瘤遗传异质性的大系列异处理乳腺癌。

Tags

免疫学 问题 130 乳腺癌 人表皮生长因子受体 2 (HER2) 异质性 组织微阵列 原位杂交 高通分子分析
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