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JoVE Journal Medicine
En musmodell av ortopedisk kirurgi att studera postoperativ kognitiv dysfunktion och vävnadsregeneration
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En musmodell av ortopedisk kirurgi att studera postoperativ kognitiv dysfunktion och vävnadsregeneration

Article DOI: 10.3791/56701-v • 08:17 min • February 27th, 2018
February 27th, 2018 •
1, 1, 2,3, 1,4
1Department of Anesthesiology, Duke University Medical Center, 2Department of Orthopaedic Surgery, Duke University Medical Center, 3Duke Molecular Physiology Institute, 4Center for Translational Pain Medicine, Duke University Medical Center

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Det här protokollet beskriver en musmodell av ortopedisk kirurgi som har använts för att studera mekanismer av postoperativ neuroinflammation och beteendeförändringar, och i kombination med parabiosis, att studera vävnadsregeneration vid åldrande.

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Medicin fråga 132 åldrande beteende cytokiner delirium healing musmodell neuroinflammation ortopedisk kirurgi parabiosis postoperativ kognitiv dysfunktion regenerering
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