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Journal / Medicine / Ganze Genom-Sequenzierung von Candida Glabrata…
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Ganze Genom-Sequenzierung von Candida Glabrata für Erkennung von Markierungen von Antimykotika Resistenz
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Ganze Genom-Sequenzierung von Candida Glabrata für Erkennung von Markierungen von Antimykotika Resistenz

Article DOI: 10.3791/56714-v • 08:46 min • December 28th, 2017
December 28th, 2017 •
*1, *1,2,3, 1,2, 1, 1, 1, 1, 1, 1, 4, 4,5, 6, 7, 1,3, 1,2,3
1Centre for Infectious Diseases and Microbiology-Public Health, Westmead Hospital, 2Centre for Infectious Diseases and Microbiology Laboratory Services, ICPMR, 3Marie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, 4Department of Microbiology and Infectious Diseases, Canberra Hospital and Health Services, Australian National University Medical School, 5Infection Management Services, Australian National University Medical School, 6Department of Microbiology and Infectious Diseases, St. Vincent's Hospital, 7Department of Infectious Diseases, Peter MacCallum Cancer Centre
* These authors contributed equally

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Diese Studie implementiert kompletten Genoms für die Analyse von Mutationen in Genen konferieren antimykotische Resistenzen in Candida Glabrata. Resistent gegen Echinocandine, Azole und 5-Flucytosine, C. Glabrata Isolate wurden sequenziert, um die Methodik zu veranschaulichen. Profile der Anfälligkeit der Isolate korreliert mit Vorhandensein oder Fehlen von spezifischen Mutation Muster in den Genen.

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Medizin Ausgabe 130 Candida Glabrata kompletten Genoms antimykotische Resistenzen Echinocandine Azole 5-Flucytosine Genom-breite Analyse
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