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JoVE Journal
Medicine

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一种基于动力学荧光的 Ca2 +动员法, 用于识别 G 蛋白偶联受体激动剂、拮抗器和构调制器
 
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一种基于动力学荧光的 Ca2 +动员法, 用于识别 G 蛋白偶联受体激动剂、拮抗器和构调制器

Article DOI: 10.3791/56780
February 20th, 2018

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Summary February 20th, 2018

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所描述的细胞检测是为鉴定 CXC 趋化因子受体 4 (CXCR4)-相互作用的代理, 抑制或刺激, 无论是竞争性或 allosterically, 细胞内 Ca2 +释放启动的 CXCR4 激活。

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