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Immunology and Infection

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JoVE Journal Immunology and Infection
Mycobacterium tuberculosis em camundongos com fluorescência de enzima do repórter de imagem
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Mycobacterium tuberculosis em camundongos com fluorescência de enzima do repórter de imagem

Article DOI: 10.3791/56801-v • 10:06 min • February 26th, 2018
February 26th, 2018 •
*1, *2, 1, 1
1Department of Microbial Pathogenesis and Immunology, Texas A&M Health Science Center, 2Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health
* These authors contributed equally

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Descrevemos a imagem óptica de camundongos infectados com Mycobacterium tuberculosis (M. tuberculosis) usando fluorescência de enzima repórter (REF). Esse protocolo proporciona uma detecção sensível e específica de M. tuberculosis em modelos animais pré-clínicos para investigação patogenia, terapêutica e vacina.

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Imunologia questão 132 pulmonar óptico lactamase vacinas modelos animais terapêutica patogênese
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