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JoVE Journal Cancer Research
En i Vivo Murine Sciatic Nerve modell Perineural invasjon
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En i Vivo Murine Sciatic Nerve modell Perineural invasjon

Article DOI: 10.3791/56857-v • 09:55 min • April 23rd, 2018
April 23rd, 2018 •
*1, *1, 1, 1, 2, 3, 1
1Department of Surgery, Memorial Sloan Kettering Cancer Center, 2Molecular Cytology Core Facility, Memorial Sloan Kettering Cancer Center, 3Department of Radiation Oncology, Mount Sinai Hospital
* These authors contributed equally

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Vi beskriver en i vivo murine modell perineural invasjon ved å injisere syngeneic kreft i bukspyttkjertelen celler i sciatic nerve. Modellen gir kvantifisering av omfanget av nerve invasjon, og støtter undersøkelse av mobilnettet og molekylære mekanismer perineural invasjon.

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Kreftforskning problemet 134 Perineural invasjon ischias nerven kreft i vivo svulst PNI mus bukspyttkjertelen adenocarcinoma
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