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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
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Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas

Article DOI: 10.3791/56880-v • 07:00 min • February 28th, 2019
February 28th, 2019 •
*1, *1, 1, 1, 2, 1, 1, 3, 1, 1, 3, 3, 3, 1, 1
1Department of Medicine and Surgery, University of Insubria, 2Department of Surgical and Morphological Science, University of Insubria, 3Department of Biotechnology and Life Science, University of Insubria
* These authors contributed equally

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Summary
Automatic Translation

Homeobox genes are regulatory genes often associated with tumors in the adult organisms. We investigated their comparative expression by immunohistochemical and real-time PCR analysis, in normal and inflammatory nasal mucosae and in sinonasal neoplasms in order to use them as possible diagnostic and therapeutic targets.

Tags

Molecular Markers OTX1 OTX2 Sinonasal Carcinomas Olfactory Neuroblastomas RNA Extraction Real-time PCR Immunohistochemistry FFPE Samples Head And Neck Tumors Xylene Alcohol Antigen-retrieval
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