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Journal / Developmental Biology / Embriyonik hematopoetik kök hücre öncüleri…
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Developmental Biology

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JoVE Journal Developmental Biology
Embriyonik hematopoetik kök hücre öncüleri endotel hücre niş ortak kültürü ile kombine sıralama tek hücre dizini kullanarak klonal analizi
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Embriyonik hematopoetik kök hücre öncüleri endotel hücre niş ortak kültürü ile kombine sıralama tek hücre dizini kullanarak klonal analizi

Article DOI: 10.3791/56973-v • 09:32 min • May 8th, 2018
May 8th, 2018 •
1,2, 1, 1, 1, 1,2
1Clinical Research Division, Fred Hutchinson Cancer Research Center, 2Department of Pediatrics, Division of Pediatric Hematology/Oncology, University of Washington School of Medicine

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Burada fare embriyonik gelişim sırasında hematopoetik kök hücre öncüleri klonal analizi için metodoloji mevcut. Endotel hücre ortak kültür ve fenotipik özellikleri ve tek hematopoetik öncüleri potansiyelini engraftment karakterize nakli ile embriyonik aort-erbezi-mesonephros bölgesinden tek hücre dizin sıralama birleştirin.

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Gelişim biyolojisi sorunu 135 hematopoetik kök hücre (HSC) pre-HSC aort-erbezi-mesonephros bölgesi (AGM) embriyonik hematopoiesis dizin sıralama tek hücre klonal analiz hematopoetik kök hücre transplantasyonu
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