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Journal / Medicine / 鼻膜 Transepithelial 电位差的标准化测量…
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鼻膜 Transepithelial 电位差的标准化测量 (NPD)
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鼻膜 Transepithelial 电位差的标准化测量 (NPD)

Article DOI: 10.3791/57006-v • 09:47 min • September 13th, 2018
September 13th, 2018 •
1, 2, 3, 4, 5, 1, 6,7
1Department of Medicine and the Gregory Fleming James Cystic Fibrosis Center, University of Alabama at Birmingham, 2Department of Pulmonology and Tuberculosis, University Medical Center Utrecht, 3Center for Experimental Medicine, Queens University, Northern Ireland, 4Hadassah Hebrew University Medical Center, Jerusalem, 5Centro Fibrosi Cistica, Azienda Ospedaliera Universitaria Integrata, 6Service de Pneumologie et Allergologie Pédiatriques and Center de Ressources et de Compétence de la Mucoviscidose, Hôpital Necker Enfants Malades, 7INSERM U 1151, Institut Necker Enfants Malades

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在这里, 我们提出了一个标准化的协议, 以测量鼻电位差 (NPD)。囊性纤维化跨膜电导调节剂 (CFTR) 和上皮性钠通道 (ENaC) 的功能是评估的变化, 在 superfusion 的解决方案, 改变离子通道活动后的鼻上皮的电压, 提供了一个结果测量。

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药物 139 期 鼻电位差异 囊性纤维化 囊性纤维化跨膜电导调节 CFTR
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