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Journal / Immunology and Infection / Ex Vivo Infektion af menneskelige lymfoide væv og …
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Immunology and Infection

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JoVE Journal Immunology and Infection
Ex Vivo Infektion af menneskelige lymfoide væv og kvindelige kønsorganer slimhinde med Human immundefekt Virus 1 og Histoculture
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Ex Vivo Infektion af menneskelige lymfoide væv og kvindelige kønsorganer slimhinde med Human immundefekt Virus 1 og Histoculture

Article DOI: 10.3791/57013-v • 11:14 min • October 12th, 2018
October 12th, 2018 •
1,2, 2, 2, 1, 2
1Department of Medicine Solna, Center for Molecular Medicine, Karolinska University Hospital, Karolinska Institutet, 2Section of Intercellular Interactions, Eunice Shriver National Institute of Child Health and Human Development, National Institutes of Health

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Infektion med humant væv med human immundefekt virus (HIV) ex vivo giver en værdifuld 3D model af virus patogenese. Her, beskriver vi en protokol for at behandle og inficere væv prøver fra menneskelige tonsiller og kvindelige kønsorganer mucosae med HIV-1 og fastholde dem i kultur på grænsefladen væske-luft.

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Immunologi og infektion spørgsmål 140 HIV human immundefekt virus 1 histoculture væv explants ex vivo infektion patogenese lymfevæv tonsiller cervikal slimhinde kvindelige forplantningsorganerne
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