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Cancer Research
Cancer Research
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マウスの脳腫瘍細胞を使用してネイティブのクロマチン免疫沈降
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Article
DOI:
10.3791/57016-v
•
09:31 min
•
January 29th, 2018
マウスの脳腫瘍細胞を使用してネイティブのクロマチン免疫沈降
January 29th, 2018
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Flor M. Mendez1, Felipe J. Núñez1,2, Rocío I. Zorrilla-Veloz3,4, Pedro R. Lowenstein1,2, Maria G. Castro1,2
1Department of Cell and Developmental Biology, University of Michigan Medical School, 2Department of Neurosurgery, University of Michigan Medical School, 3Cancer Research Summer Internship Program (CARSIP), Cancer Biology Program, University of Michigan Medical School, 4Department of Biology, University of Puerto Rico-Río Piedras Campus
Chapters
Summary
Please note that all translations are automatically generated.
Click here for the English version.
エピジェネティックなメカニズムは、神経膠腫で頻繁に変更されます。クロマチン免疫沈降は、クロマチン構造と遺伝子の転写を調節するヒストンの修正の変更から発生する神経膠腫の遺伝子変異の結果を研究に使用できます。このプロトコルはマウスの脳腫瘍細胞のネイティブのクロマチン免疫沈降をについて説明します。