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Cancer Research

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JoVE Journal Cancer Research
Radionukleid-fluorescens Reporter gen Imaging for at spore Tumor Progression i gnavere Tumor modeller
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Radionukleid-fluorescens Reporter gen Imaging for at spore Tumor Progression i gnavere Tumor modeller

Article DOI: 10.3791/57088-v • 10:04 min • March 13th, 2018
March 13th, 2018 •
1, 1, 1, 1, 1, 1, 1
1Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London

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Vi beskriver en protokol for prækliniske i vivo sporing af kræft metastaser. Det er baseret på en radionukleid-fluorescens reporter kombinerer natrium Iodid symporter, opdaget af non-invasiv [18F] tetrafluoroborate-PET, og en fluorescerende proteiner for strømlinet ex vivo bekræftelse. Metoden er anvendelig for prækliniske i vivo celle tracking uden for tumor biology.

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Kræftforskning sag 133 celle tracking reporter gen imaging natrium Iodid symporter fluorescerende proteiner positronemissionstomografi [18F] tetrafluoroborate Fluorescens mikroskopi virale gen levering
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