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Journal / Cancer Research / Radionuklid-fluorescens Reporter gen Imaging för…
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Cancer Research

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JoVE Journal Cancer Research
Radionuklid-fluorescens Reporter gen Imaging för att spåra tumör Progression i gnagare tumör modeller
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Radionuklid-fluorescens Reporter gen Imaging för att spåra tumör Progression i gnagare tumör modeller

Article DOI: 10.3791/57088-v • 10:04 min • March 13th, 2018
March 13th, 2018 •
1, 1, 1, 1, 1, 1, 1
1Department of Imaging Chemistry and Biology, School of Biomedical Engineering and Imaging Sciences, King's College London

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Vi beskriver ett protokoll för prekliniska i vivo spårning av cancer metastaser. Den är baserad på en radionuklid-fluorescens reporter kombinerar den natrium jodid symporter, upptäcks av icke-invasiva [18F] tetrafluoroborat-PET, och en fluorescerande protein för strömlinjeformad ex vivo bekräftelse. Metoden är tillämplig för prekliniska i vivo cell tracking bortom tumörbiologi.

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Cancerforskning fråga 133 Cell tracking reporter gen imaging natrium jodid symporter fluorescerande protein positronemissionstomografi [18F] tetrafluoroborat fluorescensmikroskopi viral genen leverans
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