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Journal / Cancer Research / Met behulp van 18F-FDG PET/CT beeldvorming en…
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Cancer Research

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JoVE Journal Cancer Research
Met behulp van 18F-FDG PET/CT beeldvorming en kwantitatieve histologie voor het meten van dynamische veranderingen in het Glucose metabolisme in muismodellen van longkanker
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Journal (Cancer Research)
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Journal (Cancer Research)
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Met behulp van 18F-FDG PET/CT beeldvorming en kwantitatieve histologie voor het meten van dynamische veranderingen in het Glucose metabolisme in muismodellen van longkanker

Article DOI: 10.3791/57167-v • 06:51 min • July 21st, 2018
July 21st, 2018 •
1, 2, 3, 3, 3, 1, 4, 5, 1
1Division of Pulmonary and Critical Care Medicine, University of California Los Angeles David Geffen School of Medicine, 2University of North Carolina at Chapel Hill, 3Department of Molecular and Medical Pharmacology, University of California Los Angeles, 4Andor Technology, 5Division of Orthopaedic Surgery, University of California Los Angeles David Geffen School of Medicine

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In dit protocol beschrijven we het gebruik van [18F]-2-fluoro-2-deoxy-D-glucose positron emissie tomografie en computertomografie (18F-FDG PET/CT) denkbaar voor het meten van de tumor metabole respons op de gerichte therapie MLN0128 in een Kras/Lkb1 mutant muis model van longkanker en gekoppelde imaging met hoge resolutie ex vivo autoradiografie en kwantitatieve histologie.

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Kankeronderzoek kwestie 137 18F-FDG-PET beeldvorming longkanker glycolyse LKB1 KRAS mTOR
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