Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Medicine / Surgical Swine Model of Chronic Cardiac Ischemia…
JoVE Journal
Medicine

A subscription to JoVE is required to view this content.

JoVE Journal Medicine
Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Murine Cervical Aortic Transplantation Model using a Modified Non-Suture Cuff Technique
Journal (Medicine)
Murine Cervical Aortic Transplantation Model using a Modified Non-Suture Cuff Technique
Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
Journal (Medicine)
Continuous Blood Sampling in Small Animal Positron Emission Tomography/Computed Tomography Enables the Measurement of the Arterial Input Function
 

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery

Article DOI: 10.3791/57229-v • 09:12 min • March 27th, 2018
March 27th, 2018 •
1, 1, 1, 1, 1, 2, 1
1Department of Surgery, University of Minnesota, 2Cardiology, Minneapolis VA Medical Center

Chapters

Summary
Automatic Translation

This protocol presents a surgical large animal model of chronic, single vessel ischemia that results in regional abnormalities but does not create infarct, known as hibernating myocardium. Following establishment of chronic ischemia, animals are treated with off-pump LIMA-LAD coronary artery bypass graft surgery to revascularize the ischemic tissue.

Tags

Surgical Swine Model Chronic Cardiac Ischemia Off-pump Coronary Artery Bypass Graft Surgery Revascularization Clinical Therapy Blood Flow Restoration Cardiothoracic Surgery Atherosclerotic Disease Hibernating Myocardium Large Animal Model Infarction Yorkshire Pig Intercostal Nerve Block Thoracotomy Incision Arrhythmia Lidocaine Bolus Finochietto Rib Retractor
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter