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Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats
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Invasive Hemodynamic Characterization of the Portal-hypertensive Syndrome in Cirrhotic Rats

Article DOI: 10.3791/57261-v • 09:37 min • August 1st, 2018
August 1st, 2018 •
1,2, 1,2, 1,2, 3, 1, 1,2
1Div. of Gastroenterology and Hepatology, Dept. of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 2Vienna Hepatic Hemodynamic Laboratory, Medical University of Vienna, Vienna, Austria, 3Center of Biomedical Research, Medical University of Vienna, Vienna, Austria

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Summary
Automatic Translation

Here we describe a detailed protocol for invasive measurements of hemodynamic parameters including portal pressure, splanchnic blood flow, and systemic hemodynamics in order to characterize the portal hypertensive syndrome in rats.

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Invasive Hemodynamic Characterization Portal-hypertensive Syndrome Cirrhotic Rats Advanced Liver Fibrosis Portal Hypertension Pharmacological Approaches Vascular Tone Fibrogenesis Endothelial Dysfunction Direct Measurement Of Portal Pressure Hemodynamic Parameters Hepatic Venous Pressure Gradient HVPG Sedating The Rat Isoflurane Anesthesia Endotracheal Tube Laryngeal Area Lidocaine Spray Transbuccal Suture Analgesia Injectable Anesthesia Eye Ointment Body Hair Clipping Skin Disinfection
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