Waiting
Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Genetics / Riktade nästa generations sekvensering och…
JoVE Journal
Genetics

This content is Open Access.

JoVE Journal Genetics
Riktade nästa generations sekvensering och bioinformatik Pipeline för att utvärdera genetiska determinanter av konstitutionella sjukdom
Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
Journal (Genetics)
Screening and Identification of RNA Silencing Suppressors from Secreted Effectors of Plant Pathogens
Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
Journal (Genetics)
Single-cell Gene Expression Profiling Using FACS and qPCR with Internal Standards
 
Click here for the English version

Riktade nästa generations sekvensering och bioinformatik Pipeline för att utvärdera genetiska determinanter av konstitutionella sjukdom

Article DOI: 10.3791/57266-v • 09:34 min • April 4th, 2018
April 4th, 2018 •
1,2, 3, 4, 4, 5, 4, 1, 1, 6,7, 1, 1,8, 9,10, 6,7, 4, 10,11, 4,10, 12,13, 9, 14, 10,15, 9, 9,16, 1,2
1Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, 2Department of Biochemistry, Schulich School of Medicine and Dentistry, Western University, 3Analytic and Translational Genetics Unit, Center for Genomic Medicine, Harvard Medical School, Massachusetts General Hospital, Stanley Centre for Psychiatric Research, Broad Institute of MIT and Harvard, 4Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 5School of Medicine, Faculty of Health Sciences, Queen's University, 6Faculty of Medicine, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, 7CHEO Research Institute, Faculty of Medicine, University of Ottawa, 8Department of Clinical Neurological Sciences, Western University, 9Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 10Division of Neurology, Department of Medicine, University of Toronto, 11Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, 12Department of Clinical Neurological Sciences, Schulich School of Medicine and Dentistry, Western University, 13Parkwood Institute, St. Joseph's Health Care, 14Department of Medicine, Division of Neurology, McMaster University, 15Division of Neurology, Department of Medicine, Baycrest Health Sciences, 16Canadian Partnership for Stroke Recovery Sunnybrook Site, Sunnybrook Health Science Centre, University of Toronto

Chapters

Summary
Automatic Translation

Please note that all translations are automatically generated.

Click here for the English version.

Riktade nästa generations sekvensering är en tids - och kostnadseffektiva tillvägagångssätt som blir alltmer populärt i både Sjukdomforskning och klinisk diagnostik. Protokollet beskrivs här presenterar komplex arbetsflödet behövs för sekvenseringen och bioinformatik processen används för att identifiera genetiska varianter som bidrar till sjukdom.

Tags

Genetik fråga 134 nästa generations sekvensering riktade sekvensering återställande variant ringer variant annotering konstitutionella sjukdom
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter