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Journal / Genetics / Manipulering av Ploidy i Caenorhabditis elegans
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Genetics

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JoVE Journal Genetics
Manipulering av Ploidy i Caenorhabditis elegans
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Manipulering av Ploidy i Caenorhabditis elegans

Article DOI: 10.3791/57296-v • 07:54 min • March 15th, 2018
March 15th, 2018 •
1, 1,2, 1, 1,3, 1,2,3
1Brooklyn College, Biology Department, City University of New York, 2The Graduate Center, Biology Department, City University of New York, 3Advanced Science Research Center, City University of New York

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Denne metoden tillater generering av tetraploid og triploid Caenorhabditis nematoder fra diploide belastning. Polyploid stammer generert av denne metoden har blitt brukt til å studere kromosom interaksjoner i meiotic prophase, og denne metoden er nyttig for å undersøke viktige grunnleggende spørsmål i cellen, utviklingsmessige, evolusjonær, og kreft biologi.

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Genetikk problemet 133 Polyploidy Caenorhabditis elegans rec-8 RNAi meiose endoreduplication hele-genome duplisering genomet størrelse gene dose biologiske skalering genomisk ustabilitet
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