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Optogenetic medrivning af hippocampus Theta svingninger i opfører sig mus
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Optogenetic medrivning af hippocampus Theta svingninger i opfører sig mus

Article DOI: 10.3791/57349-v • 07:33 min • June 29th, 2018
June 29th, 2018 •
1,2, 2,3, 1,2
1Systems Neurophysiology Research Group, Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, 2Behavioural Neurodynamics Group, Leibniz Institute for Molecular Pharmacology (FMP)/ NeuroCure Cluster of Excellence, 3Neuronal Circuits and Behavior Research Group, Max Planck Institute for Metabolism Research

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Vi beskriver brugen af optogenetics og elektrofysiologiske optagelser til selektiv manipulationer af hippocampus theta svingninger (5-10 Hz) i opfører mus. Effekten af rytme medrivning overvåges ved hjælp af lokale felt potentiale. En kombination af opto- og en hæmning adresser den efferente udlæsning af hippocampus synkronisering.

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Neurovidenskab sag 136 Optogenetics elektrofysiologiske optagelser i vivo adfærd theta svingning hippocampus pyramideformet celler interneurons septum locomotion farmakogenetik
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