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JoVE Journal Neuroscience
Optogenetica trascinamenti di teta Hippocampal oscillazioni nel comportarsi topi
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Optogenetica trascinamenti di teta Hippocampal oscillazioni nel comportarsi topi

Article DOI: 10.3791/57349-v • 07:33 min • June 29th, 2018
June 29th, 2018 •
1,2, 2,3, 1,2
1Systems Neurophysiology Research Group, Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, 2Behavioural Neurodynamics Group, Leibniz Institute for Molecular Pharmacology (FMP)/ NeuroCure Cluster of Excellence, 3Neuronal Circuits and Behavior Research Group, Max Planck Institute for Metabolism Research

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Descriviamo l'uso di optogenetica e registrazioni elettrofisiologiche per manipolazioni selettive delle oscillazioni di teta hippocampal (5-10 Hz) in topi si comporta. L'efficacia di trascinamento ritmo è controllata mediante potenziali di campo locale. Una combinazione di opto - e farmacogenetica inibizione indirizzi la lettura efferente di sincronizzazione hippocampal.

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Neuroscienze problema 136 optogenetica registrazioni elettrofisiologiche in vivo comportamento Teta oscillazione ippocampo cellule piramidali interneuroni setto locomozione farmacogenetica
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