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JoVE Journal Neuroscience
Optogenetic 在行为小鼠海马θ振荡中的作用
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Optogenetic 在行为小鼠海马θ振荡中的作用

Article DOI: 10.3791/57349-v • 07:33 min • June 29th, 2018
June 29th, 2018 •
1,2, 2,3, 1,2
1Systems Neurophysiology Research Group, Institute of Clinical Neuroscience and Medical Psychology, Medical Faculty, Heinrich Heine University Düsseldorf, 2Behavioural Neurodynamics Group, Leibniz Institute for Molecular Pharmacology (FMP)/ NeuroCure Cluster of Excellence, 3Neuronal Circuits and Behavior Research Group, Max Planck Institute for Metabolism Research

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我们描述使用光遗传学和电生理记录的选择操作的海马θ振荡 (5-10 赫兹) 在行为小鼠。利用局部磁场电位监测节律夹带的效果。光和遗传药理学抑制的结合解决了海马同步的传出读数。

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神经科学 问题 136 光遗传学 电生理记录,在体内 行为 θ 振荡 海马 锥体细胞 中间神经元 隔膜 运动 药物遗传学
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