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Neuroscience

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Cannula Implantation into the Cisterna Magna of Rodents
 

Cannula Implantation into the Cisterna Magna of Rodents

Article DOI: 10.3791/57378
May 23rd, 2018

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Summary May 23rd, 2018

Here we describe a protocol to perform cisterna magna cannulation (CMc), a minimally invasive way to deliver tracers, substrates and signaling molecules into the cerebrospinal fluid (CSF). Combined with different imaging modalities, CMc enables glymphatic system and CSF dynamics assessment, as well as brain-wide delivery of various compounds.

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