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JoVE Journal Medicine
Rask i Vivo evaluering av adjuvants cytotoksiske T-lymfocytter generasjon evner for vaksineutvikling
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Rask i Vivo evaluering av adjuvants cytotoksiske T-lymfocytter generasjon evner for vaksineutvikling

Article DOI: 10.3791/57401
June 19th, 2018 •
1, 1, 1, 1, 1, 1, 1, 1
1Department of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research

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June 19th, 2018

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Vi presenterer her en søknad om en standard immunologiske teknikk (CFSE farget OT-jeg spredning) skal overvåke raskt adjuvant-mediert cytotoksisk T lymfocytt (CTL) generasjon i vivo. Denne rask estimering av CTL kapasitet er nyttig for utvikling av forebyggende vaksiner mot intracellulær patogener som terapeutiske kreft vaksiner.

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