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Ved hjælp af musen oocyter at vurdere menneskelige genfunktion under meiose jeg
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Ved hjælp af musen oocyter at vurdere menneskelige genfunktion under meiose jeg

Article DOI: 10.3791/57442-v • 11:13 min • April 10th, 2018
April 10th, 2018 •
*1,2, *3, 1,2, 3
1IVI-RMA New Jersey, 2Jefferson College of Biomedical Sciences, Thomas Jefferson University, 3Department of Genetics, Rutgers, The State University of New Jersey
* These authors contributed equally

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Som de genetiske varianter forbundet med menneskelig sygdom begynder at blive afdækket, det stadig vigtigere at udvikle systemer, som hurtigt vurdere den biologiske betydning af de identificerede varianter. Denne protokol beskriver metoder til evaluering menneskeligt genfunktion under kvindelige meiose jeg bruger musen oocyter.

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Genetik spørgsmål 134 meiose oocyt aneuploidi gen-varianter kromosom segregation frugtbarhed
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